The lyrics really have the ability to pierce straight into anyone who at a point realized she had to change something about how she lived. When I interviewed the band they spoke about being Spiritually of the East but in a sense this song is rooted in America's primary fantasy-- that generally we're always free to ditch the burden of the past and start anew. The Alan Watts ref is also kewl; that's a good book.
If you would like some more ideas on why this is my favorite song of the year (and a lot of other things) you can have a copy of the first issue of Cryptophasia, which is a new print publication Liz and I have been working on for the past year and a half. It will be released by the end of the year. Just send your address to firstname.lastname@example.org and we will mail you a copy.